Fear, stress, and anxiety are some of the biggest dangers to our mental health. But like many of our unpleasant emotions, they have important functional origins; without them, we lack the motivation to flee from danger or avoid harmful behaviors. Some evidence suggests that our brain’s prefrontal cortex, an area frequently linked to behavioral control and decision-making, regulates the level of activity in our amygdala when we are faced with unpleasant stressors. Patients with lesions in specific parts of their prefrontal cortex show stronger amygdala responses when looking at distressing images. In a sense, their amygdalae are out of control. Other abnormalities in this control link between the prefrontal cortex and amygdala are characteristic of patients who suffer from depression. This raises an interesting question: Could we help people deal with stress by training them to control the activity in their amygdala when they are feeling anxious? One neuroscience technique known as neurofeedback may provide an answer.